ALTUM® treatment differs in how active ingredients are delivered. While most spicule products simply mix or coat the actives ingredients on the surface, much of it fails to reach targeted areas. ALTUM® uses a patented linker system that chemically bonds high-value peptides to the spicules, ensuring both the spicules and actives penetrate deeply into the targeted layers. Once in the skin, glutathione triggers release of the actives, ensuring accurate delivery to the target layers and maximizing absorption, regeneration, and elasticity.

ALTUM® and injectable skin boosters target different layers of the skin and therefore serve different purposes. Injectable skin boosters primarily act within the dermal layer to improve hydration and volume, whereas ALTUM® focuses on precise basal membrane targeting to support the skin’s natural renewal process and skin quality. By addressing different depths and mechanisms, these treatments can work synergistically within a multilayer approach. When combined appropriately, they may enhance overall outcomes and support more comprehensive skin improvement.

Clinical data shows that as glutathione levels rise, more peptides are released from the ALTUM® system, resulting in enhanced collagen synthesis. Nearly 90% of peptides are released within 24 hours, confirming glutathione-dependent activation. For detailed experimental data and visualization studies, please refer to the related content.(https://www.idenelprofessional.com/post/altum-science-2_how-do-we-know-if-peptides-are-delivered-into-the-skin)

Clinical trials demonstrate that ALTUM® spicules effectively penetrate beyond the stratum corneum and reach the lower epidermis — just above the dermal layer — the optimal zone for peptide delivery and skin regeneration.

Spicules are microscopic needle-like structures that form the skeletal framework of freshwater sponges. They are primarily composed of silica (SiO₂) or calcium carbonate (CaCO₃) in the form of fibrous spines.

ALTUM® spicules are precisely standardized in size and shape, measuring approximately 150–250 μm, which is comparable to the thickness of the human epidermis. This standardized size allows for accurate and reproducible delivery of active ingredients to the targeted epidermal layers with minimal invasiveness, without penetrating deeply into the dermis.

ALTUM® spicules are naturally eliminated from the skin after treatment. A significant portion detaches within 24 hours, and nearly all spicules are eliminated within 2–3 days, following the skin’s normal renewal process.

ALTUM® is a spicule-based delivery technology. GHK peptide is a key active ingredient utilized within the ALTUM® system. The core ALTUM®-based product, PEPTAXEL, contains additional supporting ingredients. For detailed product information, please refer to the link below.(https://download-files.wixmp.com/raw/5e1e13_7b35b40fcb7f40c58e6f2e50a3eaa17a.pdf?token=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJvYmoiOltbeyJwYXRoIjoiL3Jhdy81ZTFlMTNfN2IzNWI0MGZjYjdmNDBjNThlNmYyZTUwYTNlYWExN2EucGRmIn1dXSwiZGlzIjp7ImZpbGVuYW1lIjoiUHJvZHVjdCBJbmdyZWRpZW50X0VORy5wZGYiLCJ0eXBlIjoiaW5saW5lIn0sImF1ZCI6WyJ1cm46c2VydmljZTpmaWxlLmRvd25sb2FkIl0sImV4cCI6MTc3MTg5NjM0MCwianRpIjoiNThiMWEyOGItNjdlOS00NzA0LTgwZDMtYmM2ZjkyMTE4ZmI4IiwiaWF0IjoxNzcxODk1NDQwLCJpc3MiOiJ1cm46YXBwOmU2NjYzMGU3MTRmMDQ5MGFhZWExZjE0OWIzYjY5ZTMyIiwic3ViIjoidXJuOmFwcDplNjY2MzBlNzE0ZjA0OTBhYWVhMWYxNDliM2I2OWUzMiJ9.S8X6NW-rfAZ3RAlKEmy-T-c2y2p76_4PzRXy6nOz_gY)

ALTUM® technology has been evaluated through multiple study types, including: • Human clinical studies assessing improvements in wrinkles, elasticity, skin density, texture, and pores • Skin penetration and spicule shedding studies, including biopsy-based evaluations • Comparative laboratory studies using artificial skin models and porcine skin to evaluate spicule penetration and absorption across different spicule-based products ALTUM® is also protected by multiple international patents covering its technology and manufacturing process.