PEPTAXEL™ vs RFMN Split-face Comparative Test

Purpose:

The purpose of this study is to compare and analyze treatment approaches for skin texture improvement, focusing on downtime, invasiveness, and clinical outcomes.

Before

Products	PEPTAXEL™ Intensive + Brightening (1:1 mix, half used) Glutagen Skin booster applied (half)	RFMN PDRN + Hyaluronic acid injected via RFMN device (depths 0.3 mm &1.0 mm) 1cc of PLLA-based skin booster applied topically
Preparation	Lidocaine applied 10 minutes	Lidocaine applied 30 minutes

During Treatment 

Operator	Technician (manual)	Physician (RFMN device)
Time	10 minutes	5 minutes
Pain(points)	Mostly numb	Mostly numb Mild stinging 2 points on cheek/forehead
Features	No stinging or spicule penetration sensation.	Bleeding due to injection (visually noticeable)

After

Immediately	Slight redness, no noticeable sensation	Bleeding, flushed, mild stinging
With Mask	No notable reaction	Mild stinging, tingling
1 Hour	Slight stinging when touched	Embossing marks, still flushed and tingling
3 Hour	Stinging when touched (jaw area)	Slight embossing marks, no sensation
Others		Prescribed anti-inflammatory medication to prevent edema/inflammation

B&A Image

Analysis via AI 

Case 1) PEPTAXEL™

• Tone improvement: +3.7%

• Texture & Glow : +11%

• Pigmentation: -33% 

Case 2) RFMN

• Tone improvement: +2.4%

• Texture & Glow : +11%

• Pigmentation: -52.9%

  
  

1. PEPTAXEL™ improves skin tone more effectively than RFMN, while both treatments show similar gains in texture and glow.

2. Due to improvement in overall skin tone, pigmentation levels (based on color pixels) seems to have increased for both, but the pigmentation, spots increased more for RFMN.

   
   

=> PEPTAXEL™ provides similar or superior aesthetic results without injection-related bleeding or embossing, offering a less intimidating and visually favorable option for patients.

Comprehensive Comparison 

	PEPTAXEL™	RFMN
Method	Intensive + Brightening (half) Glutagen skin booster (half)	PDRN + Hyaluronic acid injection with RFMN 1cc PLLA-based skin booster
Operator	Technician (manual)	Physician (RFMN device)
Time	10 minutes Lidocaine applied 10 minutes	5 minutes Lidocaine applied 30 minutes
Pain	Mostly numb	Mostly numb; mild tingling on cheekbone/forehead (2/10)
Reaction	Slight redness, no noticeable sensation (3h) Slight stinging when touched	Bleeding, flushed, stinging & Embossing marks (3h) Embossing marks, no sensation
Improvement	Tone +3.7%, Texture/Glow +11%	Tone +2.4%, Texture/Glow +11%