What are Spicules? Spicules are microscopic needle-like structures that form the skeletal framework of freshwater sponges. Spicules controlled microstimulation helps improve skin (resilience, texture, and natural renewal) Boost self-regeneration Promotes new skin &collagen Speeds up turnover, refining texture, and elasticity. ⇒ Various products have been developed utilizing the spicules as a drug delivery system: (Surface coating, Internal channel loading, Impregnation into t

How deep can ALTUM® Peptides penetrate the skin? Choose the most accurate answer: a) Stratum Corneum b) Epidermis c) Subcutaneous Fat Layer The answer is b) “Epidermis” ALTUM® Peptides are designed to penetrate through the stratum corneum and reach the deepest part of the epidermis , right above the dermal layer. The Challenge of Precise Skin Targeting Precise delivery of active ingredients to specific depths in the skin is difficult to achieve. Topical skincare products can

Q. How do we know if peptides are delivered into the skin? A. We prove them with science — not assumption. ALTUM® Penetration Mechanism ALTUM® peptides penetrate the skin barrier. Glutathione in the skin breaks the chemical bond between the peptide and its carrier. The released peptides nourish fibroblasts in the dermis. This stimulates collagen production, improving skin elasticity. Peptide Release Test (36.5 °C, GSH concentration 0.3-0.5wt%) Clinical data shows that higher

Do you know the 500 Dalton Rule? “500 Dalton Rule” In dermatological science, the 500 Dalton Rule states that molecules with a molecular weight exceeding 500 Daltons cannot effectively penetrate the stratum corneum — the skin’s outermost barrier. *Kraeling ME, Zhou W, Wang P, Ogunsola OA. In vitro skin penetration of acetyl hexapeptide-8 from a cosmetic formulation. Cutan Ocul Toxicol. 2015 Mar;34(1):46-52. doi: 10.3109/15569527.2014.894521. Epub 2014 Apr 22. PMID: 24754410.